The expression profile and prognostic value of APE/Ref-1 and NPM1 in high-grade serous ovarian adenocarcinoma

To analyze the expression trends and clinical significance of Apurinic/Apyrimidinic Endodeoxyribonuclease 1 ( APE 1/Ref‐1) and Nucleophosmin ( NPM 1) proteins in high‐grade serous ovarian adenocarcinoma ( HGSC ). The expressions of APE 1/Ref‐1 and NPM 1 proteins in 94 patients with HGSC were determined using the immunohistochemical ( IHC ) method, and their relationships with clinicopathological features were analyzed by the χ 2 test or Fisher's...