Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.
Abstract
cope
Serine lies at the central node linking biosynthetic flux from glycolysis to glutathione synthesis and one-carbon metabolic cycle which are closely related to antioxidant capacity. The present study was conducted to determine the effects of serine supplementation on oxidative stress and its relative mechanisms.
Methods and results
Diquat treatment was performed to induce oxidative stress in mice and primary hepatocytes. The results...
Paper Details
Title
Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.
Published Date
Nov 1, 2017
Volume
61
Issue
11
Pages
1700262
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Notes
History