Aggressiveness in depression: a neglected symptom possibly associated with bipolarity and mixed features

Objective To evaluate aggressiveness during a major depressive episode ( MDE ) and its relationship with bipolar disorder ( BD ) in a post hoc analysis of the BRIDGE ‐ II ‐ MIX study. Method A total of 2811 individuals were enrolled in this multicenter cross‐sectional study. MDE patients with ( MDE ‐A, n = 399) and without aggressiveness ( MDE ‐N, n = 2412) were compared through chi‐square test or Student's t ‐test. A stepwise backward logistic...