Intracoronary Cardiac Progenitor Cells in Single Ventricle Physiology

Patients with single ventricle physiology are at high risk of mortality resulting from ventricular dysfunction. The preliminary results of the phase 1 trial showed that cardiosphere-derived cells (CDCs) may be effective against congenital heart failure.To determine whether intracoronary delivery of autologous CDCs improves cardiac function in patients with single ventricle physiology.We conducted a phase 2 randomized controlled study to assign...