Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.
Abstract
Panel-based genetic testing has identified increasing numbers of patients with pancreatic ductal adenocarcinoma (PDAC) who carry germ-line mutations. However, small sample sizes or number of genes evaluated limit prevalence estimates of these mutations. We estimated prevalence of mutations in PDAC patients with positive family history. We sequenced 25 cancer susceptibility genes in lymphocyte DNA from 302 PDAC patients in the Mayo Clinic...
Paper Details
Title
Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.
DOI
Published Date
Jan 1, 2018
Journal
Volume
20
Issue
1
Pages
119 - 127
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Notes
History