A G326E substitution in the glutamate‐gated chloride channel 3 (GluCl3) of the two‐spotted spider mite Tetranychus urticae abolishes the agonistic activity of macrocyclic lactones
Abstract
BACKGROUND The macrocyclic lactones abamectin and milbemectin are frequently used to control phytophagous mites such as Tetranychus urticae . Consequently, resistance has developed and was genetically linked with substitutions in the glutamate‐gated chloride channel (GluCl) subunits TuGluCl1 and TuGluCl3. Here, we functionally validated a G326E substitution in TuGluCl3 by functional expression in Xenopus laevis oocytes followed by two‐electrode...
Paper Details
Title
A G326E substitution in the glutamate‐gated chloride channel 3 (GluCl3) of the two‐spotted spider mite Tetranychus urticae abolishes the agonistic activity of macrocyclic lactones
Published Date
Sep 11, 2017
Journal
Volume
73
Issue
12
Pages
2413 - 2418
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