Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Volume: 50, Issue: 5, Pages: 668 - 681
Published: Apr 26, 2018
Abstract
Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide association meta-analysis based in 135,458 cases and 344,901 controls and identified 44 independent and significant loci. The genetic findings were associated with clinical features of major depression and implicated brain regions exhibiting anatomical differences in cases....
Paper Details
Title
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Published Date
Apr 26, 2018
Volume
50
Issue
5
Pages
668 - 681
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