Establishment and characterization of a novel murine model of pancreatic cancer cachexia
Volume: 8, Issue: 5, Pages: 824 - 838
Published: Jul 20, 2017
Abstract
Cachexia is a complex metabolic and behavioural syndrome lacking effective therapies. Pancreatic ductal adenocarcinoma (PDAC) is one of the most important conditions associated with cachexia, with >80% of PDAC patients suffering from the condition. To establish the cardinal features of a murine model of PDAC-associated cachexia, we characterized the effects of implanting a pancreatic tumour cell line from a syngeneic C57BL/6 KRASG12D P53R172H...
Paper Details
Title
Establishment and characterization of a novel murine model of pancreatic cancer cachexia
Published Date
Jul 20, 2017
Volume
8
Issue
5
Pages
824 - 838
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