PRMT1 regulates astrocytic differentiation of embryonic neural stem/precursor cells

Volume: 142, Issue: 6, Pages: 901 - 907
Published: Aug 2, 2017
Abstract
Arginine methylation is a post-translational modification which is catalyzed by protein arginine methyltransferases (PRMTs). Here, we report that PRMT1 is highly expressed in neural stem/precursor cells (NS/PCs) of mouse embryos, and knockdown of PRMT1 in NS/PCs suppresses the generation of astrocytes. The luciferase assay demonstrated that knockdown of PRMT1 inhibits activation of the promoter of a typical astrocytic marker gene, glial...
Paper Details
Title
PRMT1 regulates astrocytic differentiation of embryonic neural stem/precursor cells
Published Date
Aug 2, 2017
Volume
142
Issue
6
Pages
901 - 907
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