Oral delivery of vancomycin by tetraether lipid liposomes

Volume: 108, Pages: 111 - 118
Published: Oct 1, 2017
Abstract
Despite the outstanding progress in modern medicine, the oral delivery of peptide drugs is limited until today due to their instability in the gastrointestinal tract and low mucosa penetration. To overcome these hurdles, liposomes containing the specific tetraether lipid GCTE (glycerylcaldityltetraether lipid) were examined. For this purpose, the glycopeptide antibiotic vancomycin was used as model substance and liposomes were prepared by DAC...
Paper Details
Title
Oral delivery of vancomycin by tetraether lipid liposomes
Published Date
Oct 1, 2017
Volume
108
Pages
111 - 118
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