A regulatory role of androgen in ovarian steroidogenesis by rat granulosa cells
Volume: 172, Pages: 160 - 165
Published: Sep 1, 2017
Abstract
Excess androgen and insulin-like growth factor (IGF)-I in the ovarian follicle has been suggested to be involved in the pathophysiology of polycystic ovary syndrome (PCOS). Here we investigated the impact of androgen and IGF-I on the regulatory mechanism of ovarian steroidogenesis using rat primary granulosa cells. It was revealed that androgen treatment with dihydrotestosterone (DHT) amplified progesterone synthesis in the presence of FSH and...
Paper Details
Title
A regulatory role of androgen in ovarian steroidogenesis by rat granulosa cells
Published Date
Sep 1, 2017
Volume
172
Pages
160 - 165
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