Original paper

Enhanced immunization via dissolving microneedle array-based delivery system incorporating subunit vaccine and saponin adjuvant

Volume: Volume 12, Pages: 4763 - 4772
Published: Jul 1, 2017
Abstract
Purpose: To enhance the immunogenicity of the model subunit vaccine, ovalbumin (OVA) was combined with platycodin (PD), a saponin adjuvant. To reduce the toxicity of PD, OVA, and adjuvant were loaded together into liposomes before being incorporated into a dissolving microneedle array. Methods: OVA- and PD-loaded liposomes (OVA-PD-Lipos) were prepared using the film dispersion method. Their uptake behavior, toxicity to mouse bone marrow...
Paper Details
Title
Enhanced immunization via dissolving microneedle array-based delivery system incorporating subunit vaccine and saponin adjuvant
Published Date
Jul 1, 2017
Volume
Volume 12
Pages
4763 - 4772
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.