Regulation of the trafficking and the function of the metalloprotease ADAM10 by tetraspanins

Volume: 45, Issue: 4, Pages: 937 - 944
Published: Jul 7, 2017
Abstract
By interacting directly with partner proteins and with one another, tetraspanins organize a network of interactions referred to as the tetraspanin web. ADAM10 (A Disintegrin And Metalloprotease 10), an essential membrane-anchored metalloprotease that cleaves off the ectodomain of a large variety of cell surface proteins including cytokines, adhesion molecules, the precursor of the β-amyloid peptide APP or Notch, has emerged as a major component...
Paper Details
Title
Regulation of the trafficking and the function of the metalloprotease ADAM10 by tetraspanins
Published Date
Jul 7, 2017
Volume
45
Issue
4
Pages
937 - 944
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