Advanced developmental toxicity test method based on embryoid body’s area

Volume: 72, Pages: 74 - 85
Published: Sep 1, 2017
Abstract
Embryonic stem cell test (EST) evaluates the embryotoxic potential of substances and measures the half inhibition in viability of mouse embryonic stem cells (ESCs), fibroblasts (3T3 cells) and in cardiac differentiation of ESC. In this study, we suggest the developmental toxicity test method (termed EBT) applying area of embryoid bodies (EBs) instead of cardiac differentiation of EST. In the assessment of 21 substances, EB area was...
Paper Details
Title
Advanced developmental toxicity test method based on embryoid body’s area
Published Date
Sep 1, 2017
Volume
72
Pages
74 - 85
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