A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling
Abstract
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter the existing structure of the heart, leading to cardiac dysfunction. Among the complex signaling network that characterizes myocardial remodeling, the distinct processes are myocyte loss, cardiac hypertrophy, alteration of extracellular matrix homeostasis, fibrosis, defective autophagy, metabolic abnormalities, and mitochondrial dysfunction. Several...
Paper Details
Title
A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling
Published Date
Jan 1, 2017
Volume
2017
Pages
1 - 16
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