The use and abuse of Cre/Lox recombination to identify adult cardiomyocyte renewal rate and origin
Abstract
The adult mammalian heart, including the human, is unable to regenerate segmental losses after myocardial infarction. This evidence has been widely and repeatedly used up-to-today to suggest that the myocardium, contrary to most adult tissues, lacks an endogenous stem cell population or more specifically a bona-fide cardiomyocyte-generating progenitor cell of biological significance. In the last 15 years, however, the field has slowly evolved...
Paper Details
Title
The use and abuse of Cre/Lox recombination to identify adult cardiomyocyte renewal rate and origin
Published Date
Jan 1, 2018
Journal
Volume
127
Pages
116 - 128
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Notes
History