Immunomodulatory Activity ofGanoderma atrumPolysaccharide on Purified T Lymphocytes through Ca2+/CaN and Mitogen-Activated Protein Kinase Pathway Based on RNA Sequencing

Volume: 65, Issue: 26, Pages: 5306 - 5315
Published: Jun 26, 2017
Abstract
Our previous study has demonstrated that Ganoderma atrum polysaccharide (PSG-1) has immunomodulatory activity on spleen lymphocytes. However, how PSG-1 exerts its effect on purified lymphocytes is still obscure. Thus, this study aimed to investigate the immunomodulatory activity of PSG-1 on purified T lymphocytes and further elucidate the underlying mechanism based on RNA sequencing (RNA-seq). Our results showed that PSG-1 promoted T lymphocytes...
Paper Details
Title
Immunomodulatory Activity ofGanoderma atrumPolysaccharide on Purified T Lymphocytes through Ca2+/CaN and Mitogen-Activated Protein Kinase Pathway Based on RNA Sequencing
Published Date
Jun 26, 2017
Volume
65
Issue
26
Pages
5306 - 5315
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