Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients

Sepsis is a life-threatening illness with a challenging diagnosis. Current serum biomarkers are not sensitive enough for diagnosis. With the aim of finding proteins associated with sepsis, serum protein profile was compared between patients and healthy donors and serum classical inflammatory proteins were analyzed in both groups.Serum protein profiles were characterized by two-dimensional electrophoresis (2DE). Identification of the proteins was...