Osteopontin in systemic lupus erythematosus

In systemic lupus erythematosus (SLE), lupus nephritis (LN) is an important complication as an intractable condition and considered to be a prognostic factor. Based on the past reports that explain immunological functions of OPN and its relationship with autoimmune diseases such as LN or IgA nephropathy, we measured OPN full and OPN N-half in serum and urine of SLE patients and examined the possibility as a disease biomarker. OPN N-half is known...