Regulatory role of melatonin and BMP-4 in prolactin production by rat pituitary lactotrope GH3 cells
Abstract
The effects of melatonin on prolactin production and its regulatory mechanism remain uncertain. We investigated the regulatory role of melatonin in prolactin production using rat pituitary lactotrope GH3 cells by focusing on the bone morphogenetic protein (BMP) system. Melatonin receptor activation, induced by melatonin and its receptor agonist ramelteon, significantly suppressed basal and forskolin-induced prolactin secretion and prolactin mRNA...
Paper Details
Title
Regulatory role of melatonin and BMP-4 in prolactin production by rat pituitary lactotrope GH3 cells
Published Date
Aug 1, 2017
Journal
Volume
94
Pages
19 - 24
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