Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study.

Volume: 19, Issue: 1, Pages: 124 - 124
Published: Jun 6, 2017
Abstract
Increasing evidences indicate that an unbalance between tryptases and their endogenous inhibitors, leading to an increased proteolytic activity, is implicated in the pathophysiology of rheumatoid arthritis. The aim of the present study was to evaluate the impact of tryptase inhibition on experimental arthritis. Analysis of gene expression and regulation in the mouse knee joint was performed by RT-qPCR and in situ hybridization. Arthritis was...
Paper Details
Title
Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study.
Published Date
Jun 6, 2017
Volume
19
Issue
1
Pages
124 - 124
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