Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells
Abstract
We employed whole-genome RNA-sequencing to profile mRNAs and both annotated and novel long noncoding RNAs (lncRNAs) in human naive, central memory, and effector memory CD4+ T cells. Loci transcribing both lineage-specific annotated and novel lncRNA are adjacent to lineage-specific protein-coding genes in the genome. Lineage-specific novel lncRNA loci are transcribed from lineage-specific typical- and supertranscriptional enhancers and are not...
Paper Details
Title
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells
Published Date
Jul 15, 2017
Journal
Volume
199
Issue
2
Pages
547 - 558
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