Differential analysis of RNA-seq incorporating quantification uncertainty
Abstract
By using bootstraps that estimate inferential variance, the sleuth method and software provide fast and highly accurate differential gene expression analysis in an interactive Shiny app. We describe sleuth ( http://pachterlab.github.io/sleuth ), a method for the differential analysis of gene expression data that utilizes bootstrapping in conjunction with response error linear modeling to decouple biological variance from inferential variance....
Paper Details
Title
Differential analysis of RNA-seq incorporating quantification uncertainty
Published Date
Jun 5, 2017
Journal
Volume
14
Issue
7
Pages
687 - 690
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