Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels
Abstract
Skeletal muscles (∼50% of the body weight) are affected during acute and late sepsis and represent one sepsis associate organ dysfunction. Cell membrane changes have been proposed to result from a channelopathy of yet unknown cause associated with mitochondrial dysfunction and muscle atrophy. We hypothesize that the channelopathy might be explained at least in part by the expression of non-selective channels. Here, this possibility was studied...
Paper Details
Title
Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels
Published Date
Feb 1, 2018
Journal
Volume
49
Issue
2
Pages
221 - 228
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