Mapping 22q11.2 Gene Dosage Effects on Brain Morphometry
Abstract
Reciprocal chromosomal rearrangements at the 22q11.2 locus are associated with elevated risk of neurodevelopmental disorders. The 22q11.2 deletion confers the highest known genetic risk for schizophrenia, but a duplication in the same region is strongly associated with autism and is less common in schizophrenia cases than in the general population. Here we conducted the first study of 22q11.2 gene dosage effects on brain structure in a sample of...
Paper Details
Title
Mapping 22q11.2 Gene Dosage Effects on Brain Morphometry
Published Date
May 23, 2017
Journal
Volume
37
Issue
26
Pages
6183 - 6199
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