Flashbody: A Next Generation Fluobody with Fluorescence Intensity Enhanced by Antigen Binding
Abstract
Fluorescent probes are valuable tools for visualizing the spatiotemporal dynamics of molecules in living cells. Here we developed a genetically encoded antibody probe with antigen-dependent fluorescence intensity called "Flashbody". We first created a fusion of EGFP to the single chain variable region fragment (scFv) of antibody against seven amino acids of the bone Gla protein C-terminus (BGPC7) called BGP Fluobody, which successfully showed...
Paper Details
Title
Flashbody: A Next Generation Fluobody with Fluorescence Intensity Enhanced by Antigen Binding
Published Date
Jun 6, 2017
Journal
Volume
89
Issue
12
Pages
6719 - 6725
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