Construction of highly stable selenium nanoparticles embedded in hollow nanofibers of polysaccharide and their antitumor activities

Nanotechnologies have been exploited to develop safe and effective medicines and pharmaceuticals. In the present study, a novel functional nanomedicine constructed from a bioactive polysaccharide and selenium nanoparticles (SeNPs) was developed. A highly-branched β-(1→3)-D-glucan (AF1) with high anti-tumor activity was used to self-assemble hollow nanofibers with an apparent average diameter of 92 nm; Se nanoparticles were synthesized via the...