Disruption of the Gut Microbiota With Antibiotics Exacerbates Acute Vascular Rejection
Abstract
The gut microbiota influences many immunological processes but how its disruption affects transplant rejection is poorly understood.Interposition grafting of aortic segments was used to examine vascular rejection. The gut microbiota was disrupted in graft recipients using an antibiotic cocktail (ampicillin, vancomycin, metronidazole, neomycin sulfate) in their drinking water.Treatment of mice with antibiotics severely reduced total bacterial...
Paper Details
Title
Disruption of the Gut Microbiota With Antibiotics Exacerbates Acute Vascular Rejection
Published Date
Jul 1, 2018
Journal
Volume
102
Issue
7
Pages
1085 - 1095
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Notes
History