Transcriptional profile of ethylene glycol monomethyl ether-induced testicular toxicity in rats
Abstract
To clarify the molecular mechanism of ethylene glycol monomethyl ether (EGME)-induced testicular toxicity, the potential for EGME-related changes in transcript levels of genes including spermatocyte-specific genes was evaluated in the testis of rats given single dosing of EGME at 200, 600, or 2000 mg/kg. Furthermore, the contribution of decreased testicular testosterone on EGME-induced spermatocyte toxicity was investigated by comparing to...
Paper Details
Title
Transcriptional profile of ethylene glycol monomethyl ether-induced testicular toxicity in rats
Published Date
May 15, 2017
Journal
Volume
41
Issue
1
Pages
105 - 112
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