Management of diffuse low-grade gliomas in adults — use of molecular diagnostics
Abstract
Diffuse WHO grade II gliomas are histologically and genetically heterogeneous. The 2016 WHO classification redefines grade II gliomas with respect to morphological and molecular tumour alterations: grade II oligodendrogliomas are defined by the presence of whole-arm codeletion in chromosomal arms 1p/19q, whereas isocitrate dehydrogenase (IDH) mutations define subclasses of astrocytoma. Although histological grade remains useful, the prognoses of...
Paper Details
Title
Management of diffuse low-grade gliomas in adults — use of molecular diagnostics
Published Date
May 12, 2017
Journal
Volume
13
Issue
6
Pages
340 - 351
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