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doi.org/10.1016/j.gtc.2017.01.003

Hepatocellular Adenomas

Paulette Bioulac-Sage
65
,
Christine Sempoux
50
,
Charles Balabaud
54
Gastroenterology Clinics of North America3.70
Volume: 46, Issue: 2, Pages: 253 - 272
Published: Jun 1, 2017
Abstract
Hepatocellular adenomas (HCAs) are rare benign tumors. This single entity has been split into 3 subtypes corresponding to specific mutations: HNF1α-inactivated HCA; inflammatory HCA related to different mutations, all leading to activation of STAT3 pathway; and β-catenin–activated HCA related to CTNNB1 mutations. The risk of malignant transformation depends on the level of β-catenin activation, reported mainly for exon 3, including S45. It is...
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Paper Details
Title
Hepatocellular Adenomas
DOI
doi.org/10.1016/j.gtc.2017.01.003
Published Date
Jun 1, 2017
Journal
Gastroenterology Clinics of North America
Volume
46
Issue
2
Pages
253 - 272
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