Low expression of microRNA-30c promotes prostate cancer cells invasion involved in downregulation of KRAS protein

Aberrant microRNA expression is associated with tumor development. The present study aimed to elucidate the role of miR‑30c in the development of prostate cancer. Quantitative polymerase chain reaction was performed to compare miR‑30c expression in LNCaP, DU145, PC‑3 and RWPE‑1 cell lines. Lentivirus expressing miR‑30c was used to create stable overexpression cell lines to investigate the effects of miR‑30c overexpression on cell proliferation,...