Immunolocalization of Substance P and NK‐1 Receptor in ADIPOSE Stem Cells

Substance P (SP) is a neuropeptide belonging to the thachykinin peptide family. SP, after binding to its receptor, the neurokinin 1 receptor (NK1R), controls several transcription factors such as NF‐κB, hypoxia inducible factor (HIF‐1α), c‐myc, c‐fos, c‐jun, and AP‐1. SP and NK1R have a widespread distribution in both the central and peripheral nervous systems. They are also present in cells not belonging to the nervous system (immune cells,...