Genetic risk for schizophrenia and psychosis in Alzheimer disease
Abstract
Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzheimer disease (AD), affecting ~40 to 60% of individuals with AD (AD with psychosis (AD+P)). In comparison with AD subjects without psychosis, AD+P subjects have more rapid cognitive decline and poor outcomes. Prior studies have estimated the heritability of psychosis in AD at 61%, but the underlying genetic sources of this risk are not known. We...
Paper Details
Title
Genetic risk for schizophrenia and psychosis in Alzheimer disease
Published Date
May 2, 2017
Journal
Volume
23
Issue
4
Pages
963 - 972
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