Combined treatment with artesunate and bromocriptine has synergistic anticancer effects in pituitary adenoma cell lines
Abstract
Prolactinomas are the most prevalent functional pituitary adenomas. The preferred treatments for prolactinomas are dopamine agonists (DAs) such as bromocriptine (BRC), but DAs still have the challenges of tumor recurrence and drug resistance. This study demonstrates that the synergy of function and mechanism between artesunate (ART) and BRC inhibits prolactinoma cell growth in vitro. We found that low-dose ART combined with BRC synergistically...
Paper Details
Title
Combined treatment with artesunate and bromocriptine has synergistic anticancer effects in pituitary adenoma cell lines
Published Date
Apr 26, 2017
Journal
Volume
8
Issue
28
Pages
45874 - 45887
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Notes
History