Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials

// Michael Troncone 5,* , Stephanie M. Cargnelli 5,* , Linda A. Villani 2,* , Naghmeh Isfahanian 1 , Lindsay A. Broadfield 2 , Laura Zychla 6 , Jim Wright 1,6 , Gregory Pond 1 , Gregory R. Steinberg 2,3 and Theodoros Tsakiridis 1,4,6 1 Department of Oncology, McMaster University, Hamilton, Ontario, Canada 2 Department of Biochemistry, Hamilton, Ontario, Canada 3 Department of Medicine, Hamilton, Ontario, Canada 4 Department of Pathology and...