Formulation and Evaluation of Solid Self Emulsifying Drug Delivery System of Ezetimibe

Ezetimibe is the selective cholesterol absorption inhibitor. It is indicated for the treatment of primary hypercholesterolemia. The current investigation was aimed to formulate Solid self-emulsifying drug delivery system (S-SEDDS) for Ezetimibe to enhance solubility and dissolution rate which will leads to minimize the variability in absorption and it may enhance oral bioavailability of the poorly soluble drug, ezetimibe. Various modified oils,...