Original paper

Axon tension regulates fasciculation/defasciculation through the control of axon shaft zippering

eLife7.70
Volume: 6
Published: Apr 19, 2017
Abstract
While axon fasciculation plays a key role in the development of neural networks, very little is known about its dynamics and the underlying biophysical mechanisms. In a model system composed of neurons grown ex vivo from explants of embryonic mouse olfactory epithelia, we observed that axons dynamically interact with each other through their shafts, leading to zippering and unzippering behavior that regulates their fasciculation. Taking...
Paper Details
Title
Axon tension regulates fasciculation/defasciculation through the control of axon shaft zippering
Published Date
Apr 19, 2017
Journal
Volume
6
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