Stress induced nuclear granules form in response to accumulation of misfolded proteins in Caenorhabditis elegans

Environmental stress can affect the viability or fecundity of an organism. Environmental stressors may affect the genome or the proteome and can cause cellular distress by contributing to protein damage or misfolding. This study examines the cellular response to environmental stress in the germline of the nematode, C. elegans. Salt stress, oxidative stress, and starvation, but not heat shock, induce the relocalization of ubiquitin, proteasome,...