Regulation of protein‐binding activities of molecularly imprinted polymers via post‐imprinting modifications to exchange functional groups within the imprinted cavity

We prepared lysozyme‐imprinted polymers bearing modifiable sites within the imprinted cavity to introduce various functional groups via post‐imprinting modifications. For this purpose, ({[2‐(2‐methacrylamido)‐ethyldithio]‐ethylcarbamoyl}‐methoxy)acetic acid (MDTA), which has a carboxy group to interact with the target protein, lysozyme, and a disulfide linkage for post‐imprinting modifications, was used as a functional monomer. A...