816 Acetaminophen use and vitiligo risk

Background: Monobenzone is a chemical phenol used as a depigmenting agent in vitiligo. Our group has previously demonstrated that use of hair dyes, which also contain phenols, is linked to vitiligo risk. Acetaminophen (N-Acetyl-p-Aminophenol; APAP) is an over-the-counter analgesic of phenolic origin. The risk of vitiligo with systemic exposure to acetaminophen has not been evaluated. Methods: We examined the risk of vitiligo with exposures to...