An Integrin-Targeting RGDK-Tagged Nanocarrier: Anticancer Efficacy of Loaded Curcumin
Abstract
Herein we report the design and development of α 5 β 1 integrin‐specific noncovalent RGDK–lipopeptide‐functionalized single‐walled carbon nanotubes (SWNTs) that selectively deliver the anticancer drug curcumin to tumor cells. RGDK tetrapeptide‐tagged amphiphiles were synthesized that efficiently disperse SWNTs with a suspension stability index of >80 % in cell culture media. 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT)‐...
Paper Details
Title
An Integrin-Targeting RGDK-Tagged Nanocarrier: Anticancer Efficacy of Loaded Curcumin
Published Date
May 2, 2017
Journal
Volume
12
Issue
10
Pages
738 - 750
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