Brain aging and neurodegeneration: from a mitochondrial point of view
Abstract
Aging is defined as a progressive time-related accumulation of changes responsible for or at least involved in the increased susceptibility to disease and death. The brain seems to be particularly sensitive to the aging process since the appearance of neurodegenerative diseases, including Alzheimer's disease, is exponential with the increasing age. Mitochondria were placed at the center of the 'free-radical theory of aging', because these...
Paper Details
Title
Brain aging and neurodegeneration: from a mitochondrial point of view
Published Date
May 14, 2017
Journal
Volume
143
Issue
4
Pages
418 - 431
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