Caspase recruitment domain 9, microbiota, and tryptophan metabolism
Volume: 20, Issue: 4, Pages: 243 - 247
Published: Jul 1, 2017
Abstract
Inflammatory bowel diseases (IBDs) develop as a result of a combination of genetic predisposition, dysbiosis of the gut microbiota, and environmental influences. Here, we describe an example of how caspase recruitment domain 9 (CARD9), one of the numerous IBD susceptibility genes, participate to colitis susceptibility by shaping gut microbiota to produce tryptophan metabolites.Recent study showed that CARD9 mice are more susceptible to colitis...
Paper Details
Title
Caspase recruitment domain 9, microbiota, and tryptophan metabolism
Published Date
Jul 1, 2017
Volume
20
Issue
4
Pages
243 - 247
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