Genome graphs and the evolution of genome inference

Volume: 27, Issue: 5, Pages: 665 - 676
Published: May 1, 2017
Abstract
The human reference genome is part of the foundation of modern human biology and a monumental scientific achievement. However, because it excludes a great deal of common human variation, it introduces a pervasive reference bias into the field of human genomics. To reduce this bias, it makes sense to draw on representative collections of human genomes, brought together into reference cohorts. There are a number of techniques to represent and...
Paper Details
Title
Genome graphs and the evolution of genome inference
Published Date
May 1, 2017
Volume
27
Issue
5
Pages
665 - 676
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