Pyrilamine-sensitive proton-coupled organic cation (H+/OC) antiporter for brain-specific drug delivery
Abstract
Blood-brain barrier (BBB) represents the greatest challenge that hampers therapeutic molecules entering the brain. Here, we described a novel brain-specific delivery strategy targeting to pyrilamine-sensitive H+/OC antiporter to facilitate therapeutic molecules cross the BBB and penetrate into the brain. In this study, four cyclic tertiary amines were selected as the brain-targeting moieties to modify naproxen (NP), a non-steroidal...
Paper Details
Title
Pyrilamine-sensitive proton-coupled organic cation (H+/OC) antiporter for brain-specific drug delivery
Published Date
May 1, 2017
Volume
254
Pages
34 - 43
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History