Clinical characteristics of colorectal cancer as a second primary malignancy.
Published on May 20, 2015in Journal of Clinical Oncology32.956
· DOI :10.1200/JCO.2015.33.15_SUPPL.E14691
e14691 Background: Advances in cancer screening and treatment in the past 20 years have improved cancer specific survival rates, raising questions regarding second primary malignancies and the pathologic characteristics of those tumors. The aim of this study was to investigate the characteristics of colorectal (CRC) as a second primary malignancy. Methods: We reviewed the records of 1602 patients (pts) diagnosed with CRC between 2005 and 2013 in our institution. Demographics, tumor characteristics, and survival were studied. Kaplan Meier was used for survival analysis. Results: Of 1602 pts, 109 pts (6.8%) were identified with CRC as a second primary malignancy. Median (M) age at diagnosis was 71 years (40-91). There were more males than females (62% vs 38%, p < 0.0001). 86 (79%) were Caucasian. 59% of pts were current or former smokers and 13% had a history of alcohol abuse. Most common sites for primary malignancies were skin (32%), breast (19%), lymphoma (16%), prostate (14%) and thyroid (12%). Only 12 ...