Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery

Volume: 284, Issue: 18, Pages: 2905 - 2931
Published: Sep 1, 2017
Abstract
Intraflagellar transport (IFT) is a form of motor-dependent cargo transport that is essential for the assembly, maintenance, and length control of cilia, which play critical roles in motility, sensory reception, and signal transduction in virtually all eukaryotic cells. During IFT, anterograde kinesin-2 and retrograde IFT dynein motors drive the bidirectional transport of IFT trains that deliver cargo, for example, axoneme precursors such as...
Paper Details
Title
Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery
Published Date
Sep 1, 2017
Volume
284
Issue
18
Pages
2905 - 2931
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