Palladium-catalyzed intermolecular amination of unactivated C(sp3)–H bonds via a cleavable directing group
Abstract
Palladium-catalyzed intermolecular amination of unactivated C(sp3)-H bonds was developed. Using NFSI as both the amino source and the oxidant, this protocol operates under mild conditions with excellent terminal selectivity and a broad substrate scope. Moreover, the directing group can be easily removed to produce 1,2-amino...
Paper Details
Title
Palladium-catalyzed intermolecular amination of unactivated C(sp3)–H bonds via a cleavable directing group
Published Date
Jan 1, 2017
Journal
Volume
53
Issue
28
Pages
3986 - 3989
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