Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism.

Volume: 127, Issue: 4, Pages: 1414 - 1424
Published: Apr 3, 2017
Abstract
Leptin contributes to the control of resting metabolic rate (RMR) and blood pressure (BP) through its actions in the arcuate nucleus (ARC). The renin-angiotensin system (RAS) and angiotensin AT1 receptors within the brain are also involved in the control of RMR and BP, but whether this regulation overlaps with leptin's actions is unclear. Here, we have demonstrated the selective requirement of the AT1A receptor in leptin-mediated control of RMR....
Paper Details
Title
Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism.
Published Date
Apr 3, 2017
Volume
127
Issue
4
Pages
1414 - 1424
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